Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Chemotherapy drugs use different ways to stop tumor cells from dividing so they
stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from
the side effects of chemotherapy.
PURPOSE: Phase I trial to study the effectiveness of high-dose cisplatin, etoposide, and
bleomycin plus amifostine in treating children who have malignant germ cell tumors.