Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma
Status:
Completed
Trial end date:
2018-01-09
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from
dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors
to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies,
such as interferon alfa, use different ways to stimulate the immune system and stop cancer
cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to
the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma.
PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell
transplantation, biological therapy, pamidronate, and thalidomide to see how well they work
in treating patients with stage I, stage II, or stage III multiple myeloma.