Colon Cleansing Efficacy With 1L vs. 2L vs. 4L-PEG for Colonoscopy Among Inpatients
Status:
Not yet recruiting
Trial end date:
2022-05-15
Target enrollment:
Participant gender:
Summary
An adequate level of bowel preparation before colonoscopy has an extremely relevant impact on
lesion detection and procedure success. The inpatient status represents a well-known
independent predictor for inadequate colon cleansing. A recent prospective, multicentre,
Italian study among inpatients showed that an adequate colon cleansing was achieved in 60-70%
of patients, far below the ideal threshold of 90%. Interestingly, a higher rate of adequate
colon cleansing was reported for a very low-volume (1L) polyethylene glycol (PEG)-based
preparation when compared to 4L and 2L PEG-based solutions. However, this finding has to be
confirmed as the study was not controlled and the PEG-1L group was much smaller than the
other two.
Aim of the present multicenter randomized controlled study will be to assess and compare the
efficacy and safety of a novel very-low volume (1L) PEG-based preparation vs.
standard-of-care low-volume (2L) and high-volume (4L) PEG-based purge, among inpatients who
undergo colonoscopy.