Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
Maternal hypotension is the most frequent complication of a spinal Anesthesia. The prevention
of spinal hypotension appears more likely to decrease the frequency and severity of
associated adverse maternal symptoms than the treatment of established hypotension.
Intravenous fluid administration prior to spinal anesthesia for caesarean section is accepted
standard practice. The choice of fluid depends on individual and institutional habit,
material cost (crystalloid is considerably cheaper) and the perceived relative benefits and
risks. Uncommon but potentially serious adverse effect of colloids is impaired coagulation.
Although pregnancy is associated with hypercoagulability, little is known about the effects
of colloid preloading on coagulation in pregnant patients.
Phase:
Phase 2
Details
Lead Sponsor:
Assiut University
Treatments:
Anesthetics Atropine Bupivacaine Ephedrine Fibrin fragment D Hydroxyethyl Starch Derivatives Morphine Pharmaceutical Solutions Pseudoephedrine