Collection of Transplant Stem Cells for Plasma Cell Myeloma
Status:
Completed
Trial end date:
2018-01-11
Target enrollment:
Participant gender:
Summary
Background:
- One beneficial treatment for plasma cell myeloma is high-dose chemotherapy followed by stem
cell transplant. Researchers want to collect stem cells from the blood for later transplant.
Objectives:
- To collect stem cells for transplant as part of treatment for plasma cell myeloma.
Eligibility:
- Individuals at least 18 years of age who will have chemotherapy and stem cell transplant
for plasma cell myeloma.
Design:
- Participants will be screened with a physical exam and medical history. Blood and urine
samples will be collected.
- Participants will have filgrastim injections for 5 days before collection. This will
move stem cells from the bone marrow to the blood.
- Participants will have apheresis to collect the stem cells.
- Participants who need additional apheresis procedures to collect stem cells will have
filgrastim and a dose of plerixafor to improve the collection yield.