Collagen Injections for the Treatment of Acne Scars and Wrinkles

• Status: Terminated
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to find out if autologous (your own) fibroblast injections are effective for the treatment of acne scars and wrinkles.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Northwestern University

Criteria

Inclusion Criteria:

• Age 18 or over

• Bilateral acne scars or have moderate to severe wrinkles

• Subjects in good health

• Subjects has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

• Under 18 years of age

• Pregnancy or lactation

• recent Accutane use in the past 6 months

• prone to hypertrophic and keloidal scarring

• have excessively redundant skin in the treatment area or wrinkles longer than 20 cm total

• have a history of autoimmune disorders, organ transplantation, cancer not in remission, active or chronic skin disease

• have a history of basal-cell carcinoma

• have previously received autologous fibroblast treatment

• have undergone any confounding therapy in the lower two-thirds of the face within 1 year or any investigational treatment within 30 days.

• have an allergy to collagen, bovine products, local anesthetics, gentamicin, or amphotericin B

• subjects who are unable to understand the protocol or to give informed consent

• subjects with mental illness