Colla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficiency)
Status:
Unknown status
Trial end date:
2019-12-30
Target enrollment:
Participant gender:
Summary
480 pregnant patients diagnosed of silent or standard α-thalassemia, HbH disease, minor or
intermediate β-thalassemia with mild anemia will be randomly assigned to treatment group and
control group. Patients in the treatment group will be given 15 g of Colla corii asini powder
form daily for 8 weeks and followed up to 42 days postpartum while the control group will be
observed and followed up in the same period treated with placebo. Levels of hemoglobin(Hb),
reticulocyte (RET), immaturity reticulocyte (IRF), indirect bilirubin(IBIL), total
bilirubin(TBIL), lactic dehydrogenase(LDH) will be measured on three visits(baseline, week 4
and week 8). The curative effect of TCM Syndrome( week 8) and undesirable pregnancy
outcomes(42 days after giving birth) will be observed.
Phase:
Phase 4
Details
Lead Sponsor:
The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine