Inflammation in the arteries of the heart may increase the risk of cardiac death. The
proposed research seeks to identify the potential beneficial role of a safe anti-inflammatory
medication, colchicine, on reducing damage caused by opening up a blockage in the arteries of
the heart. With its quick onset of action and excellent safety profile, colchicine may have
the potential to reduce risk of major adverse events related to the heart. This research also
seeks to better understand the role of neutrophils, the most common type of inflammatory
white blood cell in the body, when there is damage to the heart.
Phase:
Phase 4
Details
Lead Sponsor:
VA Office of Research and Development
Collaborators:
New York University School of Medicine NYU Langone Health