Cognitive Impact of Paracetamol in Healthy Volunteers

• Status: Completed
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

Randomized study, double-blind, crossover, controlled versus placebo.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Collaborator: Grünenthal GmbH
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• healthy volunteers,

• aged over 18 years and not more than 25 years,

• males,

• free from any treatment in the 7 days preceding inclusion especially no use of analgesics or anti-inflammatories

Exclusion Criteria:

• Contraindications to the administration of paracetamol

• medical and/or surgical history judged by the investigator or his representative as being incompatible with the test, especially subjects with neuropathic pain

• evolutionary pathology at review for inclusion

• excessive intake of alcohol, tobacco (more than 10 cigarettes / day), coffee, tea or drinks containing caffeine (equivalent to more than 4 cups per day) or drug