Overview

Cocaine/Crack and Reduction of Compulsion With Biperiden

Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
Considering the effects of the cholinergic system on the drug reward and self-administration mechanisms, acetylcholine (Ach) may play an important role on cocaine dependence process. Then the present study aims to evaluate biperiden efficacy (a cholinergic antagonist) in attenuate compulsion, one o the main symptoms of the drug dependence.
Phase:
Phase 3
Details
Lead Sponsor:
Federal University of São Paulo
Collaborators:
Association for Psychopharmacological Research, Brazil
Nacional Conseling of Scientific Development and Technology
Treatments:
Biperiden
Biperiden lactate
Cocaine