Overview

Coadministration of Ezetimibe With Fenofibrate Versus Pravastatin Monotherapy for the Treatment of Hyperlipidaemia in HIV-infected Patients

Status:
Unknown status

Trial end date:
2012-07-01

Target enrollment:

Participant gender:

Summary

- The aim of the study is to compare the effects of coadministration of ezetimibe 10 mg/die + fenofibrate 200 mg/die versus pravastatin 40 mg/die monotherapy in HIV-infected patients treated with protease inhibitors. - Single-centre, open, randomized, controlled, prospective pilot study. - 60 patients will be enrolled in order to reach the target of 50 patients evaluable at the end of the study. The patients will be randomly assigned to a 6-month treatment with ezetimibe+fenofibrate or with pravastatin.The visit will be every month.

Phase:

Phase 4

Details

Lead Sponsor:

Ospedale di Circolo - Fondazione Macchi

Collaborator:

Merck Sharp & Dohme Corp.

Treatments:

Ezetimibe
Fenofibrate
Pravastatin