This study will help determine if CoQ10 and prednisone, alone and as a combination decrease
the decline in cardiopulmonary and skeletal muscle function that occurs in the wheelchair
confined phase of DMD. Participants who are enrolled in this study should not have taken any
corticosteroids within the last six months. This is a 13-month, prospective, randomized study
comparing a daily prednisone arm (0.75mg/kg/day), a CoQ10 arm (serum of greater than 2.5
ug/mL) and a combination arm (prednisone and CoQ10) with an enhanced standard of care arm in
wheelchair confined males age 10 to 18 years with an established DMD diagnosis.
Phase:
Phase 3
Details
Lead Sponsor:
Cooperative International Neuromuscular Research Group