Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia
Status:
Withdrawn
Trial end date:
2017-10-01
Target enrollment:
Participant gender:
Summary
Cognitive deficits are some of the most prominent and disabling symptoms of schizophrenia.
Evidence suggests that schizophrenia involves alterations to the functioning of a neural
system under the control of a brain chemical called GABA. The present project will compare
the effects of low-dose clonazepam (at a sub-sedating dose) to placebo, for effects on GABA-
modulated brain activity measured by EEG, and associated cognitive processes in people who
have schizophrenia.
Phase:
Phase 4
Details
Lead Sponsor:
Palo Alto Veterans Institute for Research
Collaborators:
Stanford University University of California, Los Angeles