Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL).

• Status: Unknown status
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Compare different corneal parameters and visual outcome of corneal collagen cross-linking (CXL) with conventional versus accelerated ultraviolet-A irradiation using riboflavin with hydroxypropyl methylcellulose.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital
• Treatments: Riboflavin

Criteria

Inclusion Criteria:

• Patients with increase of minimum of 1,0 diopter in maximum keratometry.

• Patients with increase in corneal astigmatism of minimum 1,0 diopter.

• Patients with in spherical equivalent of min 0,5 diopter.

• Patients living in Eastern Norway.

Exclusion Criteria:

• Minimum pachymetric corneal thickness (Pentacam)<360 µm.

• Central corneal scar.

• Chemical burn, serious corneal infections and ocular surface diseases.

• Pregnancy.

• Lactation.