Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
Double-blind, crossover, randomized, 3x3 Latin square, placebo-controlled study of single
intravenous dose administration of VVZ-149. To demonstrate assay sensitivity, lidocaine will
be administered as a positive control. The study will take place during a single inpatient
visit involving three separate treatment periods, each with a washout of (>16-hours. Study
drugs (VVZ-149 vs. lidocaine vs. normal saline, NS) will be administered intravenously.