Overview

Clinical Trial to Assess Rate of Onset of Bronchodilator Action in Severe Stable Chronic Obstructive Pulmonary Disease (COPD) Patients

Status:
Completed
Trial end date:
2007-08-01
Target enrollment:
0
Participant gender:
All
Summary
This trial evaluates the rate of onset of bronchodilator action of aclidinium bromide compared to placebo and tiotropium in patients with severe COPD after a single dose treatment.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
AstraZeneca
Treatments:
Bromides
Tiotropium Bromide
Criteria
Inclusion Criteria:

- Males and females aged ≥ 40 years

- Current or ex-smokers of ≥ 10 pack-year

- Clinical diagnosis of severe stable COPD

Exclusion Criteria:

- History or current diagnosis of asthma, allergic rhinitis, or atopy

- Respiratory tract infection or acute COPD exacerbation in the last 6 weeks

- Hospitalised for an acute COPD exacerbation in the last 3 months

- Evidence of contraindicated use of anticholinergic drugs