Overview

Clinical Trial on the Effectiveness of Herbal Medicinal Mixture in Parkinson Disease

Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
0
Participant gender:
All
Summary
This study was designed to evaluate the symptomatic effects or potential disease progression slowing down effect of a kind of Herbal Medicinal Mixture in Parkinson's disease (PD) patients. The treatment phase includes 12 months period of Herbal Medicinal Mixture per day or placebo and 1 month wash-out period without herbal medicine and placebo.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Fudan University
Collaborators:
China's Ministry of Health; Administration of Traditional Chinese Medicine (SATCM)
State Administration of Traditional Chinese Medicine of the People's Republic of China
Criteria
Inclusion Criteria:

- Parkinson's disease according to the UK Brain Bank criteria

- Hoehn & Yahr stadium Ⅰ~Ⅲ

- Age over 50 years

- Taking only levodopa and/or dopamine agonists when recruiting

- Consistent with the liver kidney deficiency type by Traditional Chinese Medicine (TCM)
standard

- Patients voluntarily take part in this study and signed the informed consent

Exclusion Criteria:

- Modified Hoehn-Yahr scale are higher than 4

- Had other serious illness such as liver/kidney failure, serious infection etc

- Allergic to the study drug

- Had been participated in other clinical trials during the last 3 months prior to study
inclusion.

- Taking Coenzyme Q10, MAO-B inhibitors, or vitamin E, all of which might improve the
symptom or slowdown the progression of PD.

- Taking herbal medicine that can nourish the liver and kidney by TCM standard.

- Had serious mental disorder and could not describe his/her symptom.