Clinical Trial of Topiramate for Cocaine Addiction
Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
This is an outpatient clinical trial of topiramate for addressing cocaine dependence and
reduction of cocaine associated behaviors in opiate dependent drug users maintained on
methadone treatment.
The study aims to answer whether topiramate
1. is safe and acceptable to methadone patients
2. reduces cocaine use
3. helps with collateral problems such as alcohol abuse, tobacco dependence, anxiety, PTSD
and/or pain symptoms. The study will also evaluate topiramate effect on neuro-cognitive
performance.