Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma

• Status: Recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether Lithium Carbonate combined with neo-adjuvant chemotherapy improve the prognosis of osteosarcoma

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-sen University
• Collaborators: Guangdong Provincial Hospital of Traditional Chinese Medicine; Nanfang Hospital of Southern Medical University; Qilu Hospital; Qilu Hospital of Shandong University; Shanghai 6th People's Hospital; Shenzhen Second People's Hospital
• Treatments: Lithium Carbonate

Criteria

Inclusion Criteria:

• histologically diagnosed primary classical osteosarcoma in extremities

• staging IIB

• MRI showing no skip lesion

• receive standard neo-adjuvant chemotherapy, adjuvant chemotherapy,and standard surgical treatment

Exclusion Criteria:

• a history of non-standard treatment(chemotherapy or surgery)

• secondary osteosarcoma or well-differentiated parosteal osteosarcoma

• evident dysfunction of cardia,liver and kidney, or pregnant women or women during lactation