Clinical Trial Analyzing the Efficacy of Oral Administration of Tranexamic Acid in Spine Surgery.
Status:
Completed
Trial end date:
2022-01-01
Target enrollment:
Participant gender:
Summary
Study design: Randomized control trial Purpose: Evaluate the efficacy of oral administration
of tranexamic acid (TXA) in spine surgeries to achieve blood loss reduction.
Methods. A total of 60 patients undergoing major surgery of the spine, were randomly assigned
into 2 groups. Group 1 was assigned as the control group and the other one included oral
administration of tranexamic acid 2 hours prior to surgery. Outcomes measures included
intraoperative blood loss, postoperative blood loss, hematological parameters, blood
transfusion needed, and surgical complications.