Clinical Study of Umbilical Cord Blood Mononuclear Cells (UCB-MNCs) in the Treatment of Traumatic Fracture Healing

• Status: Recruiting
• Trial end date: 2022-12-10
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to explore the effectiveness and safety of umbilical cord blood mononuclear cells in promoting traumatic fracture healing.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Qianfoshan Hospital
• Collaborator: Shandong Qilu Stem Cells Engineering Co., Ltd.

Criteria

Inclusion Criteria:

• Traumatic long bone fracture.

• Noninfectious bone nonunion, delayed bone union.

• 3 months after the operation of the fracture, the examination showed no callus growth, no signs of progressive repair at the fracture site, fracture piece space < 5mm.

• No shortening, angulation and displacement.

• There was no obvious callus growth 8 months after local bone grafting.

Exclusion Criteria:

• There are infection foci at and near the fracture end after fracture.

• 3 months after the fracture, tests showed partial callus growth.

• Combining shortening, angulation and displacement phenomena.

• Partial callus grew 8 months after local bone grafting.