Clinical Studies on Bile Acids in Barrett's Esophagus
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
This study has two major goals:
1. To determine the effects of bile salts on causing DNA injury and activating signaling
pathways that promote growth in cells from the esophagus of patients who have
gastroesophageal reflux disease (GERD)
2. To determine whether changes in bile composition induced by treating patients with a
bile salt called ursodeoxycholic acid (UDCA) can alter DNA injury, signaling pathway
activation and other types of damage in cells from the esophagus of patients who have
GERD.
Phase:
N/A
Details
Lead Sponsor:
US Department of Veterans Affairs VA Office of Research and Development