Overview

Clinical Rescue Protocol - 2

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to detect increasing medication dose results in heroin cessation for patients still using, to determine if decreasing medication dose in patients unable to tolerate medication dose increases retention, and to determine if blood levels of methadone or buprenorphine correlate with clinical response.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of California, Los Angeles
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Buprenorphine
Criteria
Inclusion Criteria:

M/F ages 21-50. Opiate dependence according to DSM-IV criteria. Self-reported use within
the last 30 days. Agreeable to conditions of study and signed informed consent.

Exclusion Criteria:

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or
nursing women. Dependence on ETOH or benzodiazepines or other sedative-hynotics. Acute
hepatitis. Other medical conditions that deem participation to be unsafe.