Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The primary objective was to evaluate the antibacterial effects of two toothpastes containing
0.3% triclosan, 2% copolymer and 0.234% sodium fluoride in a silica base as compared to a
control regular fluoride toothpaste on anaerobic and malodor bacteria 12 hours after 13 days
of product use. A secondary objective was to demonstrate that a toothpaste containing 0.3%
triclosan, 2% copolymer, 0.234% sodium fluoride and a flavor with odor-masking ingredients in
silica base (Colgate Total Toothpaste-Flavor Option 1) provides a level of antibacterial
efficacy that is "equivalent" to a toothpaste containing 0.3% triclosan, 2% copolymer, 0.234%
sodium fluoride and a regular flavor in silica base (Colgate Total Toothpaste-Flavor Option
2) after 13 days of product use.