Overview

Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry Patients

Status:
Completed
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
This study aims to evaluate blood oxygenation at the optic nerve head in relation with visual field losses observed in many Fabry patients. Data collected will allow to evaluate if there is a link between these two entities. Study will last up to 2 years during which a limited number of Fabry patients will be compared to a control group to confirm any relationship between blood flow and field losses, and to see if these results vary over time. HYPOTHESIS 1. Fabry patients will present significant differences in visual fields compared to control 2 There will be variability of the visual field defects on the long term but not on the short term 3 Blood oxygenation will be higher for Fabry patients 4 Blood volume at the optic nerve head will be the same for both groups.
Details
Lead Sponsor:
Université de Montréal
Collaborator:
Genzyme, a Sanofi Company
Treatments:
Mydriatics
Tropicamide