Overview

Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2025-06-23
Target enrollment:
Participant gender:
Summary
The aim of the study is first, to evaluate the clinical antibacterial efficacy of two different NaOCl concentrations (2,5% and 5%) under a predefined irrigant flow rate in teeth with pulp necrosis and apical periodontitis by using Real-time PCR. . Second, to evaluate the efficacy of final irrigation by assessing, if possible, a numerical definition for that "so called" as "copious irrigation". Besides the total microbial load, the antibacterial efficacy of final irrigation procedure against two different bacterial species (namely Pseudoramibacter alactolyticus and Treponema denticola) will also be examined.
Phase:
NA
Details
Lead Sponsor:
National and Kapodistrian University of Athens
Treatments:
Hydrogen Peroxide
Sodium Hypochlorite
sodium sulfate