Clinical Impact of the Withdrawal of Nitrate in Patients With Stable Angina
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Chronic treatment of stable angina with nitrates long and short action is extremely frequent.
In clinical practice the most commonly observed is a combination of anti-anginal agents,
usually including nitrates fixed in an attempt to improve the quality of life of patients,
which is not always met with success.
Numerous questions and problems are seen with chronic use of oral nitrates. From a practical
standpoint, some advocate the withdrawal of medication in stable patients, while many
physicians still hesitate to withdraw the medication by the lack of definitive information
about its consequences. In this sense there is a rationale for the attempted removal of
nitrate fixed these patients, although evidence to support this action have not been
adequately evaluated.