Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis
Status:
Completed
Trial end date:
2010-08-03
Target enrollment:
Participant gender:
Summary
Parallel, double blind, randomized, Institutional Review Board (IRB) -approved study
involving approximately 160 subjects to complete. Subjects were randomly assigned to either
the test product (Arm & Hammer Advance White Brilliant Sparkle) or the control (Crest Cavity
Protection Regular) based on baseline mean whole-mouth plaque and gingival scores and
age.Subjects brushed with their assigned dentifrice two times (2X) daily and were evaluated
for gingivitis, bleeding and plaque at Baseline and after 4-, 8-, and 12-weeks of product
use. Return to pre-study hygiene regimen for 4 weeks and final evaluation at 16 weeks.