Clinical Estradiol Trial in Women With Schizophrenia
Status:
Completed
Trial end date:
2004-12-01
Target enrollment:
Participant gender:
Summary
To investigate the 'estrogen-protection' hypothesis by comparing changes in psychotic
symptoms between one group of patients receiving standard antipsychotic drug treatment plus
placebo and a second matched group receiving standard antipsychotic drug treatment plus
100microgram estradiol patch in a double blind controlled trial.
Hypothesis : That the women receiving adjunctive estradiol will demonstrate a more rapid and
more substantial decrease in psychotic symptoms over the course of the study than the women
receiving adjunctive placebo.
Phase:
Phase 2
Details
Lead Sponsor:
Bayside Health
Collaborators:
National Alliance for Research on Schizophrenia and Depression National Health and Medical Research Council, Australia Stanley Medical Research Institute