Overview

Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance

Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate the efficacy of Suan-Zao-Ren Tang in improving sleep quality, anxiety, depression, and heroin craving among methadone-maintained persons with sleep complaints.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
China Medical University, Taiwan
Treatments:
Methadone
Criteria
Inclusion Criteria:

- aged over 20 years

- patients fulfilled the Diagnostic and Statistical Manual of Mental Disorders, Fourth
Edition criteria for opiate dependence

- patients had been receiving MMT for more than one month

- patients have sleep disturbance complains and with Pittsburgh sleep quality index
(PSQI) of greater than six

- Must be able to signed informed consent

Exclusion Criteria:

- had received any antidepressant or neuroleptic medication

- had received any TCM treatment during the previous 30 days

- had any serious physical or mental illness

- had a significant risk of suicide

- pregnancy

- inability to read and fill out the forms for the study