Clinical Efficacy and Safety of Benjakul Recipe in Treating Primary Osteoarthritis of Knee Compared With Diclofenac

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Efficacy and adverse effects of Benjakul recipe in Treating Primary Osteoarthritis of Knee Compared with Diclofenac. This study was designed as double blind, randomized controlled trial. Approval from the ethical committee of Human Research Ethics Committee of Thammasat University (No: 1 Faculty of Medicine)

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Thammasat University
• Collaborator: Thai Traditional Medical Knowledge Fund
• Treatments: Diclofenac

Criteria

Inclusion Criteria:

1. Patients with primary osteoarthritis of knee with grade I-III of Kellgren & Lawrence criteria

2. Not during breast feeding

3. Not during pregnancy with a good contraception

4. Volunteer have a normal Complete Blood Count laboratory, lipid profiles,liver function tests and renal funtion tests

5. Do not abuse drugs

6. Good cooperation

Exclusion Criteria:

1. BMI > 32

2. History of peptic ulcer, Gastroesophageal reflux disease (GERD), heart disease, liver disease or kidney disease

3. History of allergy diclofenac or allergy herbal medicine