Clinical Effectiveness of Enteric Coated(E.C.) Anise-oil on Irritable Bowel Syndrome

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Colpermin ® (Peppermint oil) is used in the treatment of Irritable Bowel Syndrome but Peppermint (Mentha x piperita) isn't native in Iran. So in this study the Enteric-Coated of Anise-oil will formulate and use in treatment of Irritable Bowel Syndrome with pain and bloating.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Shiraz University of Medical Sciences

Criteria

Inclusion Criteria:

• Meeting the Rome III Modular Questionnaire

• Patients with 50 years were required to have a colonoscopy performed within the previous 5 years

• Patients under the age of 50 years were required to have a sigmoidoscopy performed

Exclusion Criteria:

• Unable or unwilling patients to use an acceptable method of birth control

• Pregnant or nursing females

• Previous gastrointestinal or abdominal surgery (except for common causes unrelated to IBS)

• Organic disorder of the large or small bowel (e.g. ulcerative colitis, Crohn's disease)

• Mechanical obstruction

• Unexplained significant weight loss or rectal bleeding

• Diagnosis of any medical condition associated with constipation (other than IBS)

• Cancer

• Abnormal laboratory tests

• Abuse of alcohol or drugs