Overview

Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations

Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to investigate the efficacy of fractions-based herbal combinations of clearing heat and promoting blood circulation treating acute ischemic stroke and the potential mechanism of it.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Yunling Zhang
Collaborators:
Huairou Hospital of Traditional Chinese Medicine
Shandong University of Traditional Chinese Medicine
Criteria
Inclusion Criteria:

- Patients with acute ischemic stroke

- Patients with fire-heat syndrome

- Stoke onset within 48 hours

- NIHSS scores range from 5 points to 25 points

- Age from forty to seventy-five,gender not limited

- Informed and signed the consent

Exclusion Criteria:

- Cardiogenic cerebral embolism,stroke caused by other reasons or the unexplained

- Patients suitable for thrombolytic therapy(rt-PA, urokinase)

- Patients have received thrombolytic therapy

- Patients with serious diseases of heart,lungs,liver,kidneys

- Patients with bleeding or bleeding tendency recently

- Pregnant or lactating women

- Pre-existing neurological or psychiatric diseases that could confound the study
results

- Patients be allergic to alcohol,Ixeris of sonchifolia Hance components (KDZ injection)
or Panax notoginseng saponins components (Xueshuantong injection)

- Patients have participated in other clinical trials within 3 months