Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure

• Status: Not yet recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Among patients receiving dental implants, does the choice of antibiotics reduce the frequency of early implant failure ?

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jordan University Hospital
• Treatments: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids; Clindamycin; Clindamycin palmitate; Clindamycin phosphate

Criteria

Inclusion Criteria:

• Presence of a partial edentulous or edentulous alveolar ridge.

• Presence of a tooth or several teeth regarded as non-restorable with the intention of immediate implant placement.

• Periodontally healthy remaining dentition.

• Presence of a non-infected surgical site.

• Presence of enough bone and soft tissue for the implant to be placed without additional augmentation procedures.

• Must be able to swallow tablets

Exclusion Criteria:

• Patients with medical conditions that required antibiotic premedication such as prosthetic heart valve replacement, skeletal joint replacement, previous history of infective endocarditis and a history of rheumatic fever.

• Patients with metabolic diseases such as type I or II diabetes mellitus.

• Patients with past and present neoplastic disease.

• Previous radiotherapy in the head and neck area.

• Immunosuppressed patients.

• Patients with blood coagulation impairment.

• Patients with a history of systemic steroid medication or recent systemic antibiotic therapy.

• Pregnant and lactating women

• Patients with allergy to the antibiotic chosen.