Classified Treatment Strategy for De-novo Metastatic Breast Cancer After Systemic Adjuvant Therapy
Status:
Not yet recruiting
Trial end date:
2031-05-01
Target enrollment:
Participant gender:
Summary
For patients with de novo stage IV breast cancer, the current debate is whether local surgery
can improve the survival of patients. There is no clinical study on the classification after
systemic treatment of de novo stage IV breast cancer patients. In fact, the clinical stage of
tumor can change with the change of treatment. For example, the stage Ⅲ of locally advanced
breast cancer can down-staging to the stage Ⅱ after systemic treatment. Similarly, patients
with stage Ⅳ can down-staging to stage Ⅱ or stage Ⅲ after systemic treatment. At this time,
the patient can receive surgical treatment. Therefore, this study is to first treat de novo
stage IV breast cancer patients with systemic treatment, according to the response after
systemic treatment to give different treatment measures（surgery or continued systemic
treatment）. We hope that this study will provide new ideas for the treatment of de novo stage
IV breast cancer and other de novo stage IV cancers.