Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer
Status:
Terminated
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop
tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy
x-rays to damage tumor cells. Hyperthermia therapy kills tumor cells by heating them to
several degrees above body temperature. It is not yet known whether chemotherapy and
radiation therapy are more effective with or without hyperthermia therapy in treating
cervical cancer.
PURPOSE: This randomized phase III trial compared the safety and efficacy of cisplatin and
radiation therapy, together with hyperthermia therapy versus cisplatin and radiation therapy
alone in the treatment of locally advanced cervical cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Mark Dewhirst
Collaborators:
National Cancer Institute (NCI) Northwestern University