Overview

Ciprofol Titrated Induction in Reducing Post-induction Hypotension in Geriatric Patients

Status:
RECRUITING
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
Geriatric patients undergoing general anesthesia face a significant challenge, with the induction phase contributing to 50% of hypotensive events. Titrated anesthesia, involving gradual drug administration, suits elderly induction. However, propofol in titrated anesthesia tends to induce hypotension. In contrast, Ciprofol (HSK3486), a novel anesthetic, reduces hypotension during induction. This study compares hypotension incidences during induction and post-induction phases, agitation rates during recovery, perioperative awareness, postoperative delirium, and parameters in elderly patients induced with Ciprofol versus propofol through titrated anesthesia. The goal is to clarify a medically optimized anesthesia protocol for elderly patients during titrated anesthesia induction in general anesthesia.
Phase:
NA
Details
Lead Sponsor:
Sixth Affiliated Hospital, Sun Yat-sen University
Treatments:
(2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol
Propofol