Ciprofloxacin for the Prevention of Meningococcal Meningitis

• Status: Completed
• Trial end date: 2017-06-12
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the effect of antibiotic prophylaxis with ciprofloxacin, given to the contacts of meningitis cases, on the overall attack rate of meningitis during an epidemic. One third of enrolled villages will receive standard care; in one-third of villages, household contacts of meningitis cases will be offered a single dose of oral ciprofloxacin; and in one-third of villages, the entire village will be offered a single dose of oral ciprofloxacin after the notification of the first case in the village.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Epicentre
• Collaborator: Medecins Sans Frontieres, Netherlands
• Treatments: Ciprofloxacin

Criteria

Inclusion Criteria:

• Resident in a village included in the study area

Exclusion Criteria:

• Patients currently exhibiting symptoms of meningitis (to be immediately referred for further care)

• Persons with a known allergy to fluoroquinolone antibiotics.