Ciprofloxacin for the Prevention of Meningococcal Meningitis
Status:
Completed
Trial end date:
2017-06-12
Target enrollment:
Participant gender:
Summary
This study evaluates the effect of antibiotic prophylaxis with ciprofloxacin, given to the
contacts of meningitis cases, on the overall attack rate of meningitis during an epidemic.
One third of enrolled villages will receive standard care; in one-third of villages,
household contacts of meningitis cases will be offered a single dose of oral ciprofloxacin;
and in one-third of villages, the entire village will be offered a single dose of oral
ciprofloxacin after the notification of the first case in the village.