Ciprofloxacin Versus Levofloxacin in Stem Cell Transplant
Status:
Recruiting
Trial end date:
2022-03-30
Target enrollment:
Participant gender:
Summary
Ciprofloxacin and levofloxacin are both in guidelines to use for prophylaxis in autologous
and allogeneic Stem cell transplant.Ciprofloxacin was recently replaced by levofloxacin as
the preferred agent in some transplant centers. In some small retrospective studies
ciprofloxacin prophylaxis was associated with a higher rate of breakthrough gram positive
bloodstream infections. However, the optimum oral agent for antibacterial prophylaxis in
transplant recipients remains uncertain.