CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia)
Status:
Not yet recruiting
Trial end date:
2031-12-31
Target enrollment:
Participant gender:
Summary
CiproPAL is a randomised trial comparing daily ciprofloxacin with local standard care during
the induction phase of paediatric ALL treatment, and aims:
1. To assess the efficacy of ciprofloxacin prophylaxis in the reduction of infection during
the induction phase of treatment for paediatric Acute Lymphoblastic Leukaemia within the
ALLTogether-1 Trial.
2. To evaluate the impact of ciprofloxacin prophylaxis on antimicrobial resistance, both of
invasive infections and colonising organisms.
Phase:
N/A
Details
Lead Sponsor:
University College, London
Collaborator:
National Institute for Health Research, United Kingdom