Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients
Status:
Completed
Trial end date:
2017-05-22
Target enrollment:
Participant gender:
Summary
This is a pilot, prospective randomized controlled study with the primary objective to
evaluate and compare medical treatment of severe SHPT, namely oral cinacalcet versus surgical
treatment, that is, parathyroidectomy with forearm autografting, on the progression of
coronary artery and valvular calcification and left ventricular mass index in endstage renal
disease patients receiving peritoneal dialysis over 12 months. The change in arterial
stiffening, left ventricular volume, aortic valve calcium score and bone mineral density,
nutritional status and biochemical parameters, quality of life measures will be evaluated as
secondary objectives of this study.