The purpose of this research is to see if non-drug ingredients in capsules and oral solutions
affect how well drugs are absorbed. This is called "bioequivalence." Medications taken by
mouth, such as capsules and solutions, need to be absorbed into the body in order to do any
good. Capsules and solutions contain a drug, but also contain non-drug ingredients that are
called excipients or fillers. Excipients in the capsules and solutions can impact how much
drug is absorbed into the body. This is called "bioINequivalence." Capsules and solutions in
this research contain the drug cimetidine. This drug is being used since it has high water
solubility (can dissolve in water) and low ability to be absorbed.
Phase:
Phase 4
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore