Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
Cilengitide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in
chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Radiation therapy uses
high-energy x-rays to damage tumor cells. Giving cilengitide together with temozolomide and
radiation therapy may kill more tumor cells. This randomized phase I/II trial is studying the
side effects and best dose of cilengitide when given together with temozolomide and radiation
therapy and to compare how well they work in treating patients with newly diagnosed
glioblastoma multiforme