Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: High-grade squamous intraepithelial lesions of the skin near the anus are caused
by the human papillomavirus (HPV). Antiviral drugs,, such as cidofovir, act against viruses
and may stop these lesions from becoming cancer.
PURPOSE: This phase II trial is studying the side effects and how well topical cidofovir
works in treating HIV-infected patients with high-grade squamous intraepithelial lesions of
the skin near the anus.
Phase:
Phase 2
Details
Lead Sponsor:
AIDS Malignancy Consortium
Collaborators:
National Cancer Institute (NCI) The Emmes Company, LLC The EMMES Corporation