Ciclesonide vs Fluticasone Nasal Sprays in Nasal Poplyposis

• Status: Unknown status
• Trial end date: 2016-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to compare ciclesonide nasal spray once daily with fluticasone propionate aquas nasal spray BD, which is commonly prescribed in patients with nasal polyposis, in order to relieve symptoms of these patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Treatments: Ciclesonide; Fluticasone

Criteria

Inclusion Criteria:

• Individuals with the diagnosis of symptomatic nasal polyposis included.

• Objective confirmation of chronic rhinosinusitis with polyps was done by paranasal sinuses CT scan and Endoscopy.

Exclusion Criteria:

• Administration of systemic corticosteroids during last 3 months Administration of antihistamines, nasal steroids 15 days prior the including to the study.

• History of surgical treatment during last 3 month.

• History of septal deviation, severe epistaxis, cystic fibrosis, severe or non-controlled asthma, current purulent nasal infection, allergic rhinitis.

• Hypersensitivity or contraindication to steroids.

• Any positive history that was suspected to influence study parameters.

• NP requiring systemic corticosteroids or daily use of saline irrigations.