Overview

Chronotropic Incompetence in Patients With HFpEF

Status:
Completed
Trial end date:
2017-11-15
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the mechanisms of chronotropic incompetence (inability to increase heart rate with exercise) in patients with heart failure and preserved ejection fraction (HFpEF). The investigators will test both central command regulation and cardiac beta-receptor sensitivity over control of heart rate.
Phase:
N/A
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Treatments:
Dexmedetomidine
Glycopyrrolate
Isoproterenol