Overview

Chronic Plaque Psoriasis Study With Topical Formulation Of GW786034

Status:
Completed
Trial end date:
2006-02-24
Target enrollment:
Participant gender:
Summary
This study is an exploratory study to evaluate the effectiveness, safety and tolerability of three concentrations of GW786034 ointment following treatment to small areas of stable psoriatic plaques. Dosing will proceed using a microplaque approach, where small volumes of ointment will be applied under full occlusion to representative psoriatic plaques. The effectiveness of topical GW786034 treatments and controls will be explored using visual intensity assessments in addition to dermal imaging and histological surrogates of disease activity.
Phase:
Phase 1
Details
Lead Sponsor:
GlaxoSmithKline
Treatments:
Betamethasone
Betamethasone benzoate
Betamethasone sodium phosphate
Betamethasone Valerate
Betamethasone-17,21-dipropionate
Calcipotriene