Chronic Pain Risk Associated With Menstrual Period Pain
Status:
Recruiting
Trial end date:
2025-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if some women with dysmenorrhea (painful periods)
are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives
(OC) can be used to reverse this chronic pain risk.
Investigators will examine whether dysmenorrhea produces CPP via repetitive cross organ
sensitization (COS) episodes. The use of cyclical OCs to eliminate dysmenorrhea is expected
to reduce COS and decrease the risk of developing CPP.
Phase:
Phase 4
Details
Lead Sponsor:
NorthShore University HealthSystem NorthShore University HealthSystem Research Institute
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health (NIH)
Treatments:
Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination