Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study

• Status: Completed
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York University School of Medicine; NYU Langone Health
• Treatments: Azithromycin

Criteria

• Key Inclusion Criteria: List primary criteria for study inclusion (i.e. do not need to enter entire list of inclusion criteria).

1. Patient must be 50 years old or older.

2. Patient must have a smoking history of at least 20 pack-years

3. Patient must have stable COPD, GOLD 0, I and/or IIA.

4. CT of chest with evidence of emphysema

• Key Exclusion Criteria: List primary criteria for study exclusion (i.e. do not need to enter entire list of inclusion criteria).

1. FEV1 < 70%.

2. Exacerbations (defined as use of oral steroids or antibiotics) in the previous month.

3. Cardiovascular Disease defined as abnormal EKG, known or suspected coronary artery disease or congestive heart failure.

4. Diabetes mellitus

5. Renal disease

6. Liver disease

7. Lung cancer

8. ETOH use of more than >6 beers >4 mixed drinks daily