Overview

Chronic Convection Enhanced Delivery of Topotecan

Status:
Active, not recruiting

Trial end date:
2021-09-01

Target enrollment:

Participant gender:

Summary

The primary goal of this study is to establish, for the first time, safety of prolonged intracerebral convection enhanced delivery of chemotherapy in patients with recurrent high grade glioma (HGG). Secondary objectives will include determination of topotecan (TPT) distribution and radiographic tumor response with prolonged continuous intracerebral convection-enhanced delivery (CED).

Phase:

Phase 1

Details

Lead Sponsor:

Jeffrey N. Bruce

Collaborator:

National Cancer Institute (NCI)

Treatments:

Topotecan